Apps » Dual Chamber Autoinjector App

Dual Chamber Cartridge Autoinjector Modeling App

Predict stopper motion, reconstitution mixing, and injection performance for dual-chamber cartridge autoinjectors – free, directly in your browser. No download, no installation.

Built on the physics framework Veryst Engineering developed, validated, and published with Merck & Co., Inc. (Babaee, Hancock et al., 2026, Drug Delivery and Translational Research).

What it models

Four process stages – pre-reconstitution, reconstitution, priming, and injection – across two stoppers, air compression, and drug solution flow through the needle and bypass channel. Outputs: time-resolved animation, publication-quality plots, and a downloadable summary (injection time, stage timings, average flow rate, maximum diluent volume). Note: the stopper-friction law parameters were calibrated to Vetter V-LK® DCC cartridges and Datwyler FM457 stoppers, though these can be updated in the model for different choices.

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I have read and agree to the following terms: This tool provides exploration-grade estimates for early-stage screening and design exploration. Results must not be used as evidence for regulatory submissions, verification and validation, or qualification; any such work requires independent verification by validated methods. Use of this tool is not engineering, regulatory, or medical advice and creates no client or advisory relationship with Veryst Engineering. The tool is provided “as is,” without warranty of any kind, express, implied, or statutory, including accuracy, merchantability, and fitness for a particular purpose. You use it at your own risk, and to the fullest extent permitted by law, Veryst Engineering is not liable for any decision or outcome arising from its use or results. You may not copy, modify, redistribute, decompile, or reverse engineer the tool or its code. Veryst Engineering is not affiliated with, and this tool is not endorsed by, any third party whose products or names appear in it. These terms are governed by the laws of the Commonwealth of Massachusetts, and its courts have exclusive jurisdiction over any dispute. We may update these terms at any time.

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Dual Chamber Cartridge Autoinjector Modeling App

What it models

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