Dr. Matthew Hancock is a Managing Engineer at Veryst Engineering. Dr. Hancock has an extensive background in fluid mechanics and computational modeling, including microfluidics, wetting of textured surfaces, surface tension effects, heat and mass transfer, solid-fluid interaction, wave motion, and multiscale analysis. Dr. Hancock has co-authored dozens of peer-reviewed research articles in journals such as Nature Materials, Lab on a Chip, Small, and Biomaterials. To date, his research has been cited more than 2500 times.
Dr. Hancock has worked in academic, medical, and industrial settings, both as project lead and as a model-based engineering consultant. Prior to joining Veryst Engineering, Dr. Hancock was a Visiting Scientist at the Broad Institute of Massachusetts Institute of Technology and Harvard University, a postdoctoral research fellow at both Harvard Medical School and Pennsylvania State University, and an instructor in the Department of Applied Mathematics at the Massachusetts Institute of Technology.
Ph.D., Environmental Fluid Mechanics, Massachusetts Institute of Technology, 2005
M.Math., Applied Mathematics, University of Waterloo, Canada, 1999
B.Math., Applied & Pure Mathematics, University of Waterloo, Canada, 1998
Publications, Patents, Professional Service, and Editorial Activities
"Integrated Isogenic Human Induced Pluripotent Stem Cell–Based Liver and Heart Microphysiological Systems Predict Unsafe Drug–Drug Interaction," Frontiers in Pharmacology, Vol. 12, pp. 667010, 2021 (with F. T. Lee-Montiel, A. Laemmle, V. Charwat, L. Dumont, C. S. Lee, N. Huebsch, H. Okochi, B. Siemons, S. C. Boggess, I. Goswami, E. W. Miller, H. Willenbring, and K. E. Healy).
"Viscosity Model for Liquid Mixtures of Propylene Glycol, Glycerol, and Water," Industrial & Engineering Chemistry Research 2021 60 (1), 670-677 (with A. P.. Spann, A. A. Rostami, S. P. Platt, M. J. Rusyniak, R. S. Sundar, R. W. Lau, and Y. B. Pithawalla).
“An artificial vasculature for adaptive thermal control of windows,” Solar Energy Materials & Solar Cells, Vol. 117, pp. 429-436, 2013 (with B. D. Hatton, I. Wheeldon, M. Kolle, J. Aizenberg, and D. E. Ingber).
“Anisotropic wetting on structured surfaces,” MRS Bulletin, Vol. 38, pp. 391-396, 2013 (with M. C. Demirel).
“Bioinspired directional surfaces for adhesion, wetting, and transport,” Advanced Functional Materials, Vol. 22, pp. 2223-2234, 2012 (with K. Sekeroglu and M. C. Demirel).
“WaveAR: A software tool for calculating parameters for water waves with incident and reflected components,” Computers & Geosciences, Vol. 46, pp. 38-43, 2012 (with B. J. Landry, C. C. Mei, and M. H. García).
“Designer hydrophilic regions regulate droplet shape for controlled surface patterning and 3D microgel synthesis,” Small, Vol. 8, pp. 393-403, 2012 (with F. Yanagawa, Y.-H. Jang, J. He, N. N. Kachouie, H. Kaji, and A. Khademhosseini).
“Biomimetic tissues on a chip for drug discovery,” Drug Discovery Today, Vol. 17, pp. 173-181, 2012 (with A. M. Ghaemmaghami, H. Harrington, H. Kaji, and A. Khademhosseini).
“Multi-gradient hydrogels produced layer by layer with capillary flow and crosslinking in open microchannels,” Lab on a Chip, Vol. 12, pp. 659-661, 2012 (with F. Piraino, G. Camci-Unal, M. Rasponi, and A. Khademhosseini).
“An integrated microfluidic device for two-dimensional combinatorial dilution,” Lab on a Chip, Vol. 11, pp. 3277-3286, 2011 (with Y.-H. Jang, S. B. Kim, S. Šelimović, W. Y. Sim, H. Bae, and A. Khademhosseini).
“Anisotropic material synthesis by capillary flow in a fluid stripe,” Biomaterials, Vol. 32, pp. 6493-6504, 2011 (with F. Piraino, G. Camci-Unal, M. Rasponi, and A. Khademhosseini).
“Surface tension driven gradient generation in a fluid stripe for bench-top and microwell applications,” Small, Vol. 7, pp. 892-901, 2011 (with J. He, J. F. Mano, and A. Khademhosseini).
“Microfluidic synthesis of composite cross-gradient materials for investigating cell–biomaterial interactions,” Biotechnology & Bioengineering, Vol. 108, pp. 175-185, 2011 (with J. He, Y. Du, Y. Guo, B. Wang, H. Shin, J. Wu, D. Li, and A. Khademhosseini).
“An engineered anisotropic nanofilm with unidirectional wetting properties,” Nature Materials, Vol. 9, pp. 1023-1028, 2010 (with N. A. Malvadkar, K. Sekeroglu, W. J. Dressick, and M. C. Demirel).
"Biomimetic gradient hydrogels for tissue engineering,” Canadian J. Chemical Engineering, Vol. 88, pp. 899-911, 2010 (with S. Sant, J. P. Donnelly, D. Iyer, and A. Khademhosseini).
“Convection-driven generation of long-range material gradients,” Biomaterials, Vol. 31, pp. 2686-2694, 2010 (with Y. Du, J. He, J. Villa-Uribe, D. M. Cropek, and A. Khademhosseini).
“A hollow sphere soft lithography approach for long-term hanging drop methods,” Tissue Engineering C, Vol. 16, pp. 249-259, 2010 (with W. G. Lee, D. Ortmann, H. Bae, and A. Khademhosseini).
“Cell confinement in patterned nanoliter droplets in a microwell array,” J. Biomedical Materials Research A, Vol. 93A, pp. 547-557, 2010 (with L. Kang, M. Brigham, and A. Khademhosseini).
“Interface directed self-assembly of cell-laden microgels,” Small, Vol. 6, pp. 937-944, 2010 (with B. Zamanian, M. Masaeli, J. W. Nichol, M. Khabiry, H. Bae, and A. Khademhosseini).
“Cell docking in double grooves in a microfluidic channel,” Small, Vol. 5, pp. 1186-1194, 2009 (with M. Khabiry, B. G. Chung, H. Chandra Soundararajan, Y. Du, D. M. Cropek, W. G. Lee, and A. Khademhosseini).
“Rapid generation of spatially and temporally controllable long-range concentration gradients in a microfluidic device,” Lab on a Chip, Vol. 9, pp. 761-767, 2009 (with Y. Du, J. Shim, M. Vidula, E. Lo, B. G. Chung, J. Borenstein, M. Khabiry, D. M. Cropek, and A. Khademhosseini).
“Sandbar formation under surface waves: Theory and experiments,” J. Geophysical Research, Vol. 113, pp. C07022 (with B. J. Landry and C. C. Mei).
“Note on sediment sorting in a sandy bed under standing water waves,” Coastal Engineering, Vol. 54, pp. 694-699, 2007 (with B. J. Landry and C. C. Mei).
“Weakly nonlinear surface waves over a random seabed,” J. Fluid Mechanics, Vol. 475, pp. 247-268, 2003 (with C. C. Mei).
“Late-time asymptotic dynamics of Bianchi VIII cosmologies,” Classical & Quantum Gravity, Vol. 20, pp. 1757-1777, 2003 (with J. T. Horwood, D. The, and J. Wainwright).
“Surface gravity waves over a two-dimensional random seabed,” Physical Review E, Vol. 66, pp. 016611, 2002 (with J. H. Pihl and C. C. Mei).
“Fluid pipes,” J. Fluid Mechanics, Vol. 466, pp. 285-304, 2002 (with J. W. M. Bush).
“Non-tilted Bianchi VII0 models - the radiation fluid,” Classical & Quantum Gravity, Vol. 17, pp. 3119-3134, 2000 (with U. S. Nilsson and J. Wainwright).
“Asymptotic self-similarity breaking at late times in cosmology,” Classical & Quantum Gravity, Vol. 16, pp. 2577-2598, 1999 (with J. Wainwright and C. Uggla).
“On the isotropy of the Universe: do Bianchi VIIh cosmologies isotropize?” Classical & Quantum Gravity, Vol. 15, pp. 331-350, 1998 (with J. Wainwright, A. A. Coley, and G. F. R. Ellis).
“Nanomaterials in Tissue Engineering: Fabrication and Applications,” Woodhead Publishing (Elsevier), 2013 (edited with A. K. Gaharwar, S. Sant, and S. A. Hacking).
Patents and Patent Applications
“Systems and methods fabricating a microchannel vascular network device and seeding a microchannel,” US Patent Application No. 20210071145A1, filed June 18, 2020 (with J. P. Vacanti, B. Byambaa, C. Comer, T. Lieberthal, T. Sahakyants, A. Spann, C. Neville).
“Apparatuses, systems, and methods for adjusting fluid lenses,” US Patent No. 10754145, Aug. 25, 2020. (with A. J. Ouderkirk, K. M. Smyth, J. M. Cooke, K. C. Hatzilias, L. Lu, N. H. Elabbasi, R. Sharma, B. Bastani).
“Additive manufacture of complex implantable living devices,” US Patent Application No. 20190358367A1, filed May 28, 2019 (with J. P. Vacanti, M. S. Oliver, A. P. Spann).
“Apparel thermo-regulatory system,” US Patent Application No. 20170340037A1, filed May 26, 2017 (with C. Bailey, K. D. Baschak, O. A. Echols, S. L. Hansen, L. Hartman, R. P. Hurd, A. Parkinson, S. K. Redell, D. Sagan, S. L. Sokolowski, S. B. Brown).
“Cryo-treatment in a microfluidic device,” WO Patent Application 2014085801A1, filed December 2, 2013 (with R. Nicol, F. Piraino, and S. Steelman).
“A microfluidic device and uses thereof,” WO Patent Application 2011035185A3, filed September 17, 2010 (with A. Khademhosseini, M. Khabiry, B. G. Chung, and Y. Du).
“Method and system for generating spatially and temporally controllable concentration gradients,” US Patent Application No. 20110300570, filed November 16, 2009 (with A. Khademhosseini and Y. Du).
Professional Service and Editorial Activities
Member, Scientific Committee, COMSOL Conference, Boston, MA, October 2013.
Co-organizer, Bioinspired Directional Surfaces Symposium, MRS Fall Meeting, Boston, MA, November 2012
Ad-hoc reviewer for Advanced Functional Materials, Analytical Chemistry, ChemPhysChem, Europhysics Letters, Industrial & Engineering Chemistry Research, Journal of Fluid Mechanics, Lab on a Chip, PLoS ONE, Physical Review E, Physical Review Letters.