Scott C. Grindy, Ph.D.

Engineer

Dr. Scott Grindy is an Engineer at Veryst Engineering. Dr. Grindy’s expertise is in the design of functional polymeric materials through materials chemistry and structure.  He has worked extensively with polymeric materials such as soft hydrogels, thermoplastics, photo-curing systems, and biodegradable polymers.  Dr. Grindy has experience using both mechanical characterization such as DMA and rheology and analytical methods such as FTIR, DSC, and HPLC to analyze materials in areas such as drug delivery, implantable biomedical devices, adhesives, and consumer products to understand how material structure and chemistry drives performance.

Prior to joining Veryst, Dr. Grindy was a Postdoctoral Research Fellow in the Harris Orthopaedics Laboratory at Massachusetts General Hospital and Harvard Medical School.  In the Harris Lab, Dr. Grindy focused on the design of the next-generation ultra-high molecular weight polyethylene used as the articulation bearing surface in hip and knee replacement surgeries.  He has also worked on topics as varied as the analysis of nickel superalloy aircraft engine materials, method development for high-throughput quantum mechanical calculations, and analysis of biofilm disruption.

Education

Ph.D., Materials Science and Engineering, Massachusetts Institute of Technology, 2017

B.S., Materials Science and Engineering, Northwestern University, 2012

Selected Publications

“Delivery of Bupivacaine from UHMWPE and Its Implications for Managing Pain After Joint Arthroplasty,” Acta Biomaterialia, Volume 93, pp. 63-73, 2019 (with D. Gil, J. V. Suhardi, O. K. Muratoglu, H. Bedair, and E. Oral).

“Antimicrobial Effect of Anesthetic-Eluting Ultra-High Molecular Weight Polyethylene for Post-Arthroplasty Antibacterial Prophylaxis,” Journal of Orthopaedic Research, Volume 34, Issue 4, pp. 981-990, 2019 (with D. Gil, O. K. Muratoglu, and E. Oral).

“Control of Hierarchical Polymer Mechanics with Bioinspired Metal-Coordination Dynamics,” Nature Materials, Volume 14, Issue 12, pp. 1210-1216 (with R. Learsch, D. Mozhdehi, J. Cheng, D. G. Barrett, Z. Guan, P. B. Messersmith, and N. Holten-Andersen).

“Bio-Inspired Metal-Coordinate Hydrogels with Programmable Viscoelastic Material Functions Controlled by Longwave UV Light,” Soft Matter, Volume 13, Issue 22, pp. 4057-4065, 2017 (with N. Holten-Andersen).

“Engineering Elasticity and Relaxation Time in Metal-Coordinate Cross-Linked Hydrogels,” Macromolecules, Volume 49, Issue 21, pp. 8306-8312, 2016 (with M. Lenz and N. Holten-Andersen).

“Tuning Dynamic Mechanical Response in Metallopolymer Networks Through Simultaneous Control of Structural and Temporal Properties of the Networks,” Macromolecules, Volume 49, Issue 17, pp. 6310-6321, 2016 (with D. Mozhdehi, J. A. Neal, Y. Cordeau, S. Ayala, N. Holten-Andersen, and Z. Guan).

“Dual Role for 1, 2, 4, 5-Tetrazines in Polymer Networks: Combining Diels–Alder Reactions and Metal Coordination to Generate Functional Supramolecular Gels,” ACS Macro Letters, Volume 4, Issue 4, pp. 458-461, 2015 (with K. Kawamoto, J. Liu, N. Holten-Andersen, and J. A. Johnson).

“Suprametallogels and Uses Thereof,” U.S. Patent No. 10023536B2, issued 2016 (with J. A. Johnson, N. Holten-Andersen, K. Kawamoto, A. V. Zhukhovitskiy).

“Mucins Trigger Dispersal of Pseudomonas Aeruginosa Biofilms,” NPJ Biofilms and Microbiomes, Volume 4, Issue 1, p. 23, 2018 (with J. Y. Co, G Cárcamo-Oyarce, N. Billings, K. M. Wheeler, N. Holten-Andersen, and K. Ribbeck).

“Charge Influences Substrate Recognition and Self-Assembly of Hydrophobic FG Sequences,” Biophysical Journal, Volume 113, Issue 9, pp. 2088-2099, 2017 (with W. G. Chen, J. Witten, N. Holten-Andersen, and K. Ribbeck).

“White-Light-Emitting Lanthanide Metallogels with Tunable Luminescence and Reversible Stimuli-Responsive Properties,” Journal of the American Chemical Society, Volume 137, Issue 36, pp. 11590-11593, 2015 (with P. Chen, Q. Li, and N. Holten-Andersen).

“Approaching Chemical Accuracy with Density Functional Calculations: Diatomic Energy Corrections,” Physical Review B, Volume 87, Issue 7, 075150, 2013 (with B. Meredig, S. Kirklin, J. E. Saal, and C. Wolverton).

How can we help?