This course—now taking place over three days—will cover most of the structural analysis capabilities in COMSOL Multiphysics including large deformations, linear and nonlinear material models, contact mechanics, solver settings and convergence issues, multiphysics coupling, and best practices.&nbs
This course—now taking place over three days—will review the physics areas relevant to medical devices and cover the efficient use of COMSOL Multiphysics to solve problems in the medical device industry. It covers modeling challenges specific to medical devices, such as biological material
A simple way of mixing small volumes (microliters or milliliters) of reagents is by repeatedly dispensing and withdrawing solution from a microwell or tube. In this case study, we used a two-phase multiphysics simulation with coupled fluid flow and mass transfer to analyze the efficacy of this active mixing process.
Bubbles trapped in microchannels can distort the fluid flow and impact the device performance. Veryst developed a multiphase CFD model to predict the effect of geometry and surface properties on the likelihood of bubble entrapment.
How fast does a Calrod heat up and how high are the stresses during heating? To answer these questions Veryst Engineering developed a coupled electric-thermal-structural multiphysics model of the Calrod, accounting for conduction, convection, and radiation.
Removing reagents or sample from a previous processing step via a wash cycle is a common challenge in microfluidic assays used in diagnostic, genomic, biomedical, pharmaceutical and other applications. This case study shows how finite element simulations may be used to predict and optimize wash cycle performance.
Controlling spatial variations in chemical concentration is important for designing and operating many microfluidic devices across a wide range of industries and applications including diagnostics, genomics, and pharmaceutics. In this case study, we show how simulations may be used to quantify and control concentration gradients in microfluidic devices.
Thermal ablation is a minimally invasive way to treat tumors, and simulating the physics of ablation can help in the design of ablation devices. Veryst designed and simulated a catheter-based acoustic ablation device relying on acoustic pressure waves to heat tissue to induce necrosis.
For several of the electromagnetics interfaces provided with COMSOL Multiphysics, a single layer shell feature, the “Transition Boundary Condition,” is available. Veryst created custom expressions to extend this feature for multiple layers. In this case study we discuss the implementation of this new functionality, and the advantages of using such shells for electromagnetic modeling.
When a thin structure is immersed in a fluid, its natural frequencies, mode shapes, and damping characteristics may be significantly affected by the fluid. Predicting the dynamic behavior in this case requires a structural-acoustic analysis.
The main environmental factor affecting a premature neonate is thermo-neutrality, as the baby is incapable of regulating and maintaining his/her body temperature at a constant level. Veryst developed a computational model of heat transfer inside an infant incubator to optimize its design.
Laminar static mixers are often employed in industrial environments when the mixing of two or more fluids is required. However, their performance is impossible to analyze with a pure CFD approach. Veryst, in collaboration with Nordson EFD, developed a unique computational modeling tool to evaluate and optimize the design of such mixers.
Both the efficiency and life of an LED bulb drop when operated at high temperature. Given the wide range of possible shapes and sizes of heat sinks, Veryst Engineering developed a rapid and effective tool to compare design alternatives and estimate LED temperatures.
Controlling the size of lipid nanoparticles (LNPs) in small-batch pharmaceutical processes is critical for delivery efficiency in mRNA vaccines, cancer therapies, and point-of-care diagnostics. In this case study, Veryst simulated solvent mixing and LNP self-assembly kinetics in a microfluidic mixer to predict the size distribution of LNPs across a range of process flow conditions.
Veryst developed a coupled CFD mass transfer model to predict a microfluidic mixer configuration appropriate for mixing pure and salt water channels.