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A cornerstone for ophthalmic therapy, intravitreal injection must overcome unique challenges: ensuring patient comfort, safeguarding delicate retinal tissues, and delivering medication accurately to specific intraocular targets. Key design metrics—including injectate volume, dispersion, injection force, needle gauge, and intraocular pressure rise—must be precisely optimized. In this case study, Veryst leverages multiphysics CFD simulation to predict, manage, and enhance device safety and performance for innovative ocular drug delivery.

Capillary filling, the autonomous wicking of liquids through hydrophilic microchannels driven by surface tension and wettability, enables pump-free, precise fluid handling in microfluidic devices for the biotechnology, MedTech, semiconductor, and chemical processing fields. In this case study, we present advanced simulations of capillary filling and its dependence on wettability, quantified by the contact angle. Such simulations inform product and process design decisions to enhance efficiency, reliability, and scalability.

Reconstituting freeze-dried drug products in autoinjectors requires rapid and uniform dissolution to ensure accurate dosing and patient safety. Veryst used multiphysics simulation to model the mixing and dissolution process, revealing how factors like particle size, concentration, and viscosity impact reconstitution speed—guiding the optimization of the device, formulation, and operating protocols.