This course—now taking place over three days—will cover most of the structural analysis capabilities in COMSOL Multiphysics including large deformations, linear and nonlinear material models, contact mechanics, solver settings and convergence issues, multiphysics coupling, and best practices. Th
This course—now taking place over three days—will review the physics areas relevant to medical devices and cover the efficient use of COMSOL Multiphysics to solve problems in the medical device industry. It covers modeling challenges specific to medical devices, such as biological material model
Bubbles trapped in microchannels can distort the fluid flow and impact the device performance. Veryst developed a multiphase CFD model to predict the effect of geometry and surface properties on the likelihood of bubble entrapment.
Efficient ventilation can reduce a building’s energy consumption and minimize airborne pathogen transmission in hospital rooms. Veryst used computational fluid dynamics (CFD) to simulate ventilation in a hospital room as well as the dispersion of particles and droplets.
Fast mixing of reagents in microfluidic channels and devices is important for DNA sequencing, mRNA vaccine production in small-batch pharmaceutical processes, and point-of-care diagnostics. In this case study, Veryst used computational fluid dynamics simulations to evaluate the mixing performance of three commonly used microfluidic mixers.
Removing reagents or sample from a previous processing step via a wash cycle is a common challenge in microfluidic assays used in diagnostic, genomic, biomedical, pharmaceutical and other applications. This case study shows how finite element simulations may be used to predict and optimize wash cycle performance.
Cohesive zone modeling is a powerful tool for predicting delamination in adhesively bonded structures. Veryst engineers use their expertise in experimental and computational fracture mechanics to calibrate cohesive zone models for accurate prediction of adhesive failure.
Controlling spatial variations in chemical concentration is important for designing and operating many microfluidic devices across a wide range of industries and applications including diagnostics, genomics, and pharmaceutics. In this case study, we show how simulations may be used to quantify and control concentration gradients in microfluidic devices.
A commonly encountered failure mode in microfluidic devices is delamination between adjacent device layers. Veryst examined the influence of control channel geometry on the delamination pressure of a pneumatic microfluidic valve using finite element analysis.
Thermal ablation is a minimally invasive way to treat tumors, and simulating the physics of ablation can help in the design of ablation devices. Veryst designed and simulated a catheter-based acoustic ablation device relying on acoustic pressure waves to heat tissue to induce necrosis.
Manufacturing variations are of critical importance in MEMS design. In this MEMS gyroscope case study, Veryst created an approach to look at the effect of a range of manufacturing variations on MEMS devices using the same mesh. We also use semi-analytic equations to enable scalable modeling of the gyroscope electrostatic actuation and pick-off (which senses the motion produced by rotation).
For several of the electromagnetics interfaces provided with COMSOL Multiphysics, a single layer shell feature, the “Transition Boundary Condition,” is available. Veryst created custom expressions to extend this feature for multiple layers. In this case study we discuss the implementation of this new functionality, and the advantages of using such shells for electromagnetic modeling.
Red bloods cells may be damaged in medical devices due to high shear stresses induced by their flow through the device. Veryst simulated turbulent flow of a converging-diverging nozzle specified in an FDA benchmark study, incorporating different hemolysis models to determine which areas of the device may damage red blood cells.
Polymers exhibit significant temperature-dependent mechanical response. Veryst tested a PEEK material at multiple temperatures and calibrated the PolyUMod® Three Network (TN) material model for finite element simulation.
This case study demonstrates the testing and calibration of a polycarbonate material at a high strain rate of 1000 sec-1. The testing was done with the Split Hopkinson Pressure Bar (SHPB) system and the calibration is performed with the MCalibration® software, originally developed by Veryst Engineering.