Microfluidics

Case study

Active Mixing in a Microwell by Repetitive Pipetting
A simple way of mixing small volumes (microliters or milliliters) of reagents is by repeatedly dispensing and withdrawing solution from a microwell or tube. In this case study, we used a two-phase multiphysics simulation with coupled fluid flow and mass transfer to analyze the efficacy of this active mixing process.
Bubble Entrapment in Microchannels
Bubbles trapped in microchannels can distort the fluid flow and impact the device performance. Veryst developed a multiphase CFD model to predict the effect of geometry and surface properties on the likelihood of bubble entrapment.
Chemical Carryover in Microfluidic Devices
Removing reagents or sample from a previous processing step via a wash cycle is a common challenge in microfluidic assays used in diagnostic, genomic, biomedical, pharmaceutical and other applications. This case study shows how finite element simulations may be used to predict and optimize wash cycle performance.
Concentration Gradients in Microfluidic Devices
Controlling spatial variations in chemical concentration is important for designing and operating many microfluidic devices across a wide range of industries and applications including diagnostics, genomics, and pharmaceutics. In this case study, we show how simulations may be used to quantify and control concentration gradients in microfluidic devices.
Delamination in Microfluidic Valves
A commonly encountered failure mode in microfluidic devices is delamination between adjacent device layers. Veryst examined the influence of control channel geometry on the delamination pressure of a pneumatic microfluidic valve using finite element analysis.
Microfluidic Mixer Concentration Profile
Veryst developed a coupled CFD mass transfer model to predict a microfluidic mixer configuration appropriate for mixing pure and salt water channels.
Oxygen Transport and Cellular Uptake in a Microchannel
Oxygen transport is a key factor in the design of cell culture systems such as organs-on-a-chip, multiphysiological systems, and bioreactors. In this case study, we use multiphysics simulation to analyze oxygen transport and cellular uptake in a model microchannel bioreactor.
Theoretical and numerical analysis of low-voltage cascade electroosmotic pumps
Electroosmotic (EO) pumps are driven purely by electric fields and have no moving parts. Cascading EO pumps reduces voltage requirements. Veryst used computational fluid dynamics (CFD) and semi-analytical equivalent circuit theory to analyze the complex behavior of these pumps.

Service

Fluids
Veryst offers state-of-the-art consulting in the design and analysis of gaseous and fluid systems and products. We employ advanced CFD analysis to solve problems involving fluid mixing, multiphase flow, phase change, non-Newtonian fluids, and microfluidic effects.
MEMS & Sensors Reliability
Veryst assists clients with MEMS and sensors consulting through failure analysis, reliability, lifetime prediction, yield enhancement, micro-contamination analysis, and microfluidics and multiphysics simulations. We provide a synergistic approach of combining analytical characterization, empirical studies, and simulation. Veryst scientists are well versed in packaging reliability as well.
Microfluidics

Veryst offers a comprehensive approach to solving problems in microfluidic device development.

Simulation & Analysis

Veryst provides expertise in many aspects of simulation and analysis for use in product design, manufacturing processes, and failure analysis.  This includes modeling and analysis involving polymer materials, multiphysics modeling, finite element analysis, computational fluid dynamics, and system

News item

COMSOL blog features Veryst's work modeling, simulating bubble entrapment
Veryst’s modeling and simulation work was featured in a COMSOL blog titled “Preventing Bubble Entrapment in Microfluidic Devices Using Simulation.”  The blog describes how Veryst modeled different microchannel geometries and simulated bubble movement, providing insight that can be used to improve the design of microfluidic devices. 
There's a new engineer at Veryst
Veryst is pleased to welcome a new member to its engineering team! Dr. Matthew Hancock, has an extensive background in fluid mechanics and model-based engineering, including microfluidics, wetting of textured surfaces, surface tension effects, heat/mass transfer, solid-fluid interaction, wave motion, and multiscale analysis.

Event

Gold Sponsor of COMSOL Conference 2013
Veryst Engineering is proud to have been a Gold Sponsor of COMSOL’s premier event: COMSOL Conference 2013 Boston.

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