Medical Devices

Veryst has deep expertise in consulting to the medical device industry, with experience that covers all phases of the product development process as well as failure analysis.
 

Manufacturing and Design

Biomedical stents
Biomedical stents

We work with medical device firms on design and manufacturing both to solve problems and accelerate development.  We use advanced engineering tools that include applied finite element analysis, fabrication and joining technologies, material selection, and testing methodologies.

Our work ranges from developing new constitutive models that capture absorbable polymers' viscoelasticity to assisting with the development of MEMS medical devices; from modeling the transdermal drug delivery process to developing applications ("apps") that simulate RF tissue ablation.

Veryst offers unique expertise in advanced finite element analysis (FEA) of medical devices and implants.  We use a combination of commercial finite element codes (Abaqus, ANSYS, COMSOL Multiphysics) supplemented by proprietary material models for thermosets, thermoplastics, elastomers, and foams (PolyUMod®).  Our proprietary models provide both greater accuracy and insight than is possible with commercial codes alone. 
 

Regulatory Support

Clients have used our analyses from early stage concept development through regulatory submissions (FDA 510k and PMA and CE Mark).  We have provided finite element analysis support for Class I, II, and III device regulatory documents, and helped design validation experiments for fatigue and strength for FDA submissions.  We have also worked with firms in preparing responses associated with recall actions on topics of fatigue, contamination, strength, creep, and long-term testing.
 

Failure Analysis

Veryst’s world-leading capabilities in design, testing, manufacturing, and failure analysis also make us uniquely suited to investigate the failure of medical devices during development as well as post-production issues and root cause analysis.

 

Class III Devices

Implanted Devices

Veryst has used its expertise in nonlinear material behavior and large deformation simulation to assist medical device companies in the development of implanted devices such as stents, orthopedic implants, meshes, and fixation devices.
 

Vascular Implants

Veryst’s material modeling and FEA capabilities are used in the design and development of vascular implant systems, such as cardiovascular stents, valves, and grafts.  Our advanced capabilities provide valuable information allowing for the optimization of designs early in the design process.  With our unique material modeling capabilities in our PolyUMod software library, Veryst is well-equipped to consider important advanced material behaviors, such as:

Cardiovascular Stent Simulation
Cardiovascular stent simulation
  • Nonlinear viscoplasticity
  • Shape-memory material behavior
  • Material anisotropy due to manufacturing processes
  • Effects of fatigue due to pulsatile loading
  • Time-dependent material degradation of absorbable material


 

Orthopedic Implants

Veryst’s FEA capabilities are used in the design of orthopedic implants, such as hip and knee joint replacements.  Advanced material models for ultra-high molecular weight polyethylene (UHMWPE), developed by engineers at Veryst, are used to analyze important load-bearing components and accurately evaluate the performance of new designs.

Total Knee Replacement
Total knee replacement

 

Spinal Implants

Our FE analyses are applicable in the design and failure investigation of spinal implant systems, including spinal fixation systems and advanced artificial disc or disc repair systems.

Spinal Cross-Section
Spinal cross-section

 

Advanced Biomaterials

Veryst’s advanced FE capabilities make us uniquely suited to assist in the development of advanced biomaterials, including:

  • Synthetic and natural scaffold materials for tissue generation and wound healing applications
  • Advanced medical adhesives and cements
  • Materials for absorbable medical fasteners (sutures, screws, plates etc.)

 

Veryst’s proprietary PolyUMod software library enables simulations beyond the reach of those using commercial finite element codes.

PLA Stress Strain Plot
Stress-strain behavior of polylactic acid (PLA)

 

Class II Devices

Veryst has supported medical devices companies in the design, failure analysis, and regulatory submission of numerous devices, including:

Catheters

Catheters kink when passed around corners or tight radii within the body.  Veryst’s FE analysis expertise has been used to complement a test program to investigate the factors contributing to catheter kinking.
 

FEA of catheter kinking
FEA of catheter kinking


 

Patient Lifts and Supports

Veryst uses its analysis capabilities to investigate the design and reliability of patient lift and support systems.  Veryst uses finite element analysis to assist in the design of critical components, frequently of systems comprising a wide variety of engineering materials including steel, aluminum, polymers, and composites.
 

Analysis of Patient Support System
Analysis of patient support system


 

Medical Devices Incorporating Fluid Flow

Veryst uses its multiphysics analysis capabilities to analyze combined thermal-fluid devices such as the gas humidification devices used with insufflation equipment.

Multiphysics Modeling of a Gas Humidification System
Multiphysics modeling of a gas humidification system

You may also like...

Multiphysics Analysis for Medical Devices Using COMSOL Multiphysics

Mar 26-27, 2020

This two-day course will cover the efficient use of COMSOL Multiphysics to solve problems in the medical device industry.  It covers modeling challenges specific to medical devices, and several examples including tissue ablation and a cardiovascular application.  The class includes technical lectures, hands-on COMSOL examples, and assistance on specific models from course registrants.

Transdermal Drug Delivery

Veryst developed a diffusion model accounting for the different layers of the human skin in order to predict the drug concentration profile of a transdermal drug delivery process.

How can we help?