Chemical Reactors & Bioreactors

Veryst assists clients in solving challenging problems involving chemical reactors and bioreactors.  We employ advanced simulation and multiphysics tools in addition to analytical models to address the many layers of coupled physics – fluid flow, heat transfer, chemical reactions, thermodynamics, and porous media – that are often involved in reacting systems.  Our engineers have applied their deep understanding of these underlying physical phenomena in applications such as reactor scale-up, focusing on the associated changes in the rates of relevant transport processes, distributor manifold design, and prediction of mass transfer in multiphase systems.

Chemical Reactors and Bioreactors
Mixing in a stirred tank reactor


  • Laminar and turbulent flow
  • Multiphase flow
  • Heat transfer
  • Mass transfer
  • Flow in porous media
  • Colloids and particulate flows
  • Chemical reactions



  • Biotechnology
  • Pharmaceutical
  • Batteries
  • Consumer products
  • Food products

Veryst Capabilities

  • Reactor scale-up
  • Multiphase flows (droplets, bubbles)
  • Microfluidic reactors
  • Lab-on-chip devices

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Chemical Carryover in Microfluidic Devices

Removing reagents or sample from a previous processing step via a wash cycle is a common challenge in microfluidic assays used in diagnostic, genomic, biomedical, pharmaceutical and other applications. This case study shows how finite element simulations may be used to predict and optimize wash cycle performance.

Active Mixing in a Microwell by Repetitive Pipetting

A simple way of mixing small volumes (microliters or milliliters) of reagents is by repeatedly dispensing and withdrawing solution from a microwell or tube. In this case study, we used a two-phase multiphysics simulation with coupled fluid flow and mass transfer to analyze the efficacy of this active mixing process.

Scaling Yield and Mixing in Chemical Reactors

Scaling chemical reactions from the lab to pilot or production requires a detailed understanding of the physical system, which frequently involves heat transfer, mass transfer, reaction kinetics, and fluid flow. This case study illustrates how multiphysics simulations can support design decisions involved in scaling up chemical reactors.

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