Microfluidics & Millifluidics
Multiphysics simulation support for industrial microfluidic and millifluidic device & process development across industries from drug delivery and bioprocessing to consumer products and energy applications.
Getting a microfluidic device right means predicting how fluids, particles, chemicals, and flexible structures behave at a scale where intuition often fails. When a design underperforms, or you’re not sure it will work before you build it, Veryst helps you understand the physics and find a path forward.
Our engineers combine analytical models, computational simulation, and hands-on device testing to solve real microfluidic design problems. We work with clients across industries including medical devices, drug delivery, bioprocessing, consumer products, and energy, often from early concept through validated, manufacturable prototypes.
How Veryst Helps
Microfluidic devices fail in ways a CAD model won’t show you: uneven mixing, clogging, leaks, delamination, or a formulation that behaves differently once it’s inside a device. Veryst helps you find the root cause and gives you practical design and manufacturing recommendations.
- Device and process design: Model micropumps, valves, channel networks, and manifolds to predict flow, mixing, and structural performance before you build.
- Drug delivery and combination products: Simulate injection devices, needle-free microjets, transdermal patches, and implantable systems to optimize dose delivery and device performance.
- Bioprocessing and biomanufacturing: Improve mixing, particle formation, and drying steps for mRNA vaccines, chromatography, and other lab- and production-scale processes.
- Energy and electrochemical systems: Optimize flow and species transport in batteries, fuel cells, electrolyzers, and micro heat exchangers.
- Core physics expertise: Apply deep knowledge of surface tension, rheology, fluid-structure interaction, and heat transfer to any microfluidic challenge.
Contact us to discuss how microfluidics simulation can help solve your device design, delivery, or manufacturing challenge.
- Biomedical Engineering: Microphysiological Systems, Organs-on-a-Chip, and Implantable Devices
3D-printed implantable liver device. Courtesy 3D BioLabs LLC. Relevant case studies
- Combination Products and MedTech: Drug Delivery and Injection Systems
Predicted reconstitution process steps in a dual-chamber autoinjector. Relevant case studies
- Merck & Co.: Dual-Chamber Autoinjector Modeling
- Biora Therapeutics: Breakthrough Smart Pill Development
- Shear Jamming in Dense Suspensions
- Optimizing Subcutaneous Drug Delivery via Multiphysics Simulation
- Optimizing Intravitreal Drug Delivery via Multiphysics Simulation
- Transdermal Drug Delivery
- Transdermal Permeation Enhancers
- Bioprocessing and Chemical Manufacturing
Simulation of lipid nanoparticle (LNP) precipitation in a serpentine microfluidic mixer for lab-scale mRNA vaccine production, and corresponding LNP size-distribution. Relevant case studies
- Energy and Electrochemical Systems
Simulated current density distribution in PEM electrolyzer stack. Relevant case studies
- Microfluidic and Millifluidic Devices
Simulation of a micropump based on tilted flexible flaps. Relevant case studies
- Micropump Mechanism
- Capillary Filling in a Microfluidic Channel
- Chaotic Mixing in Microfluidic Devices
- Active Mixing in a Microwell by Repetitive Pipetting
- Microfluidic Mixer Concentration Profile
- Bubble Entrapment in Microchannels
- Fluid Flow Through Porous Media
- Simulation of Droplet Formation
- Delamination in Microfluidic Valves
- Shear Jamming in Dense Suspensions
- Core Fluid Physics
Every application on this page draws on the same underlying physics. Here’s a closer look at the core phenomena our engineers model most often.
Mixing in Microfluidic and Millifluidic Devices
Chaotic mixing in a microfluidic serpentine mixer. Relevant case studies
- Heat Transfer and Exchange
Predicted temperature in a micro heat exchanger Relevant case studies
- Capillary Flow, Surface Tension & Wetting
Relevant case studies
- Fluid-Structure Interaction
Simulation of a micropump based on tilted flexible flaps. Relevant case studies
- Complex Fluids and Rheology
Jamming of a dense suspension in a syringe needle. Relevant case studies
- Electrochemistry
Simulated oxygen gas distribution in the anodic flow channels resulting from water electrolysis. Relevant case studies
Intellectual Property
Veryst prioritizes client confidentiality, so most of our work stays private. In select cases, client-focused work is disclosed through journal publications or patents. A few examples relevant to microfluidics and multiphysics device design include:
- US 12,351,827 B2 — Systems and methods fabricating a microchannel vascular network device and seeding a microchannel (3D BioLabs LLC)
- US 10,754,145 B1 — Apparatuses, systems, and methods for adjusting fluid lenses (Meta Platforms Technologies LLC)
- US 11,330,851 B2 — Apparel thermoregulatory system (Nike Inc.)
We Don’t Just Deliver Solutions; We Explain the "Why" Behind Them
Browse our library of webinars, whitepapers, and blogs to learn more from our experts on advanced simulations, material modeling, and physical model validations.
Related Case Stories
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